To quantify the accuracy of five equations to predict the metabolic cost of load carriage under ecologically valid military speed and load combinations. Thirty-nine male serving infantry soldiers completed thirteen, 20-minute bouts of overground load carriage comprising of two speeds (2.5 and 4.8 km·h-1) and six carried equipment load combinations (25, 30, 40, 50, 60, and 70 kg), with 22 also completing a bout at 5.5 km·h-1 carrying 40 kg. For each speed-load combination the metabolic cost was measured using the Douglas bag technique, and compared to the metabolic cost predicted from five equations; Givoni & Goldman, 1971 (GG), Pandolf et al. 1997 (PAN), Santee et al. 2001 (SAN), American College of Sports Medicine 2013 (ACSM), and the Minimum-Mechanics Model (MMM), Ludlow & Weyand, 2017. Comparisons between measured and predicted metabolic cost were made using repeated measures ANOVA and Limits of Agreement. All predictive equations, except for PAN, under-predicted the metabolic cost for all speed-load combinations (p<0.001). The PAN equation accurately predicted metabolic cost for 40 and 50 kg at 4.8 km·h-1 (p>0.05), under-predicted metabolic cost for all 2.5 km·h-1 speed-load combinations as well as 25 and 30 kg at 4.8 km·h-1, and over-predicted metabolic cost for 60 and 70 kg at 4.8 km·h-1 (p<0.001). Most equations (GG, SAN, ACSM, MMM) under-predicted metabolic cost while one (PAN) accurately predicted at moderate loads and speeds, but over-predicted or under-predicted at other speed-load combinations, indicating that caution should be applied when utilising these predictive equations to model military load carriage tasks.