Liver Health: Evidence-based considerations for nutritional therapy and personalised lifestyle support.

Liver health is essential for a variety of physiological processes, including transport and storage of many micronutrients. Nutritional factors, including nutrient deficiency, calorie excess and excess alcohol intake can contribute to the development of a range of liver disorders. Metabolic Associated Steatotic Liver Disease (MASLD) affects an estimated 25% of the global population and the prevalence of liver disorders is predicted to increase substantially. This narrative review aims to provide a useful summary of common liver disorders, as well as a summary of the evidence on the role of key macro and micronutrients, dietary and lifestyle factors and the role of the microbiome in supporting liver health. It also includes a brief review of the utility of laboratory assessments for evaluating different aspects of liver health. It aims to guide evidence-based decision-making by nutrition and healthcare practitioners when recommending personalised nutrition interventions to support liver health.